My general method is install MBAM and Spybot S&D
Run a rootkit check.
Install Avast!Free if they don't have anything better.
Clean up and reset Browsers.
Run All-in-one windows repair tool if things like windows firewall turned off.
Run windows update.
Am I missing a trick ? Should I be doing anything else?
What do you do?
I use D7II, and will run the following tools. I don't necessarily run them in a specific order, as it is down to what the machine has on it.
HitManPro - Very quick scan that pulls up numerous infections quickly. Also is
very good at finding hidden proxy servers.
MalwareBytes - Good at most things, but takes a while to run
RogueKiller - Very good at finding leftover malware remnants - Will reboot your machine when finished
Autoruns - just to check after the above.
If there's still anomalies, then Windows AIO repair - full repair. Then the usual Windows Updates, Anti Virus/Malware updates (I will sell them a copy of BitDefender), defrags, cleanup of temp files, check missing shortcuts, CCleaner etc.. Most of it automated through D7II
As I said, not always run in this order. Sometimes I do more, sometimes less. Depends on what the infection is.
Haven't used SpyBot S&D in 10 years - it just doesn't do an efficient job any more IMO.
Andy