I just cleaned the worst (for me anyways) tdss4 infections. Kaspersky tdsskiller nailed it everytime, scanned with Kasp and BD live, MSE, Mbam, and a manual look. Everything was coming up clean. But just touch Windows update (which would fail) in the browser and bam, the mbr is reinfected. tdsskiller again, everything is clean. And clean after multiple reboots. I go in and reset ie 8, check for bho's and other crap. It is clean. Nothing out of the ordinary. Hit WU again, bam mbr virus. So finally re-run tdsskiller, then perform inplace upgrade (XP machine), hit WU, WU works again, and it is staying clean. What ever was reinfecting it must have got whacked by the repair-reload.