No
As the description says:
"Editor's note: These variations can change rapidly and be difficult to remove. Often you need multiple programs to effectively eliminate these infections. If this does not work for you, we suggest using Malwarebytes Anti-Malware and or reading our Malware Removal Guide."
I completely agree.
The two specialized tools that I'd trust is Confickerfix if you know for sure it's conficker, and TDSS Killer which is the only thing so far that can quickly remove tdlr4.